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EDUCATION - B.S. 1999, Massachusetts Institute of Technology
Biology - M.S., 2003, University of Wisconsin-Madison
Biochemistry
RESEARCH EXPERIENCE - Whitehead Institute, MIT, 2/1999-2001
Advisor - Richard A. Young, PhD
Project - Determining the transcription profile of S. cerevisiae in response to pH stress, and development of novel genome-wide technologies - Massachusetts Institute of Technology, 9/1998-2/1999
Advisor - Stephanopulos
Project - Investigation of signal transduction in prostate cancer - Massachusetts Institute of Technology, 1/1998-8/1998
Advisor - Alexander Rich, PhD
Project - Mammalian nuclear mRNA editing - Massachusetts Institute of Technology, 9/1997-6/1998
Advisor - Vicki Kelley
Project - Worked on autoimmune disease
CAREER GOAL - I am working on the elucidation of the regulation of transcriptome.
PUBLICATIONS - Kanin EI, Kipp RT, Kung C, et al. Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis. Proc Natl Acad Sci U S A. 104:5812-5817, 2007.
- Raffaelle M, Kanin EI, Vogt J, Burgess RR, Ansari AZ. Switching and Stochastic Release of Sigma Factors from RNA polymerase in vivo. Mol Cell 20:357-366, 2005
- Herring CD, Raffaelle M, Allen TE, Kanin EI, Landick R, Ansari AZ, Palsson BO. Immobilization of Escherichia coli RNA Polymerase and Location of Binding Sites by Use of Chromatin Immunoprecipitation and Microarrays. J Bacteriol 187:6166-6174, 2005.
- Causton HC, Ren B, Koh SS, Harbison CT, Kanin E, Jennings EG, Lee TI, True HL, Lander ES, Young RA. Remodeling of yeast genome expression in response to environmental changes. Mol Biol Cell. 12:323-37, 2001.
- Ren B, Robert F, Wyrick JJ, Aparicio O, Jennings EG, Simon I, Zeitlinger J, Schreiber J, Hannett N, Kanin E, Volkert TL, Wilson CJ, Bell SP, Young RA. Genome-wide location and function of DNA binding proteins. Science 290:2306-9, 2000.
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