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EDUCATION - B.S. 2002, University of New Mexico
Biochemistry
RESEARCH EXPERIENCE - Sandia National Laboratories, Biomolecular Materials and Interfaces Department, 2002- 2003
Advisor - George Bachand, PhD
Project - Functionalization of silicon surfaces with receptors for biomolecular recognition in the development of diagnostic, biological sensors. - Sandia National Laboratories, Biomolecular Materials and Interfaces Department, 2002- 2003
Advisor - Darryl Sasaki, PhD
Projects - Fabrication of bio-compatible surfaces using self-assembled monolayers for microfluidic studies, Tethering of synthetic lipid membranes onto modified silicon surfaces. - University of New Mexico, Biochemistry & Molecular Biology Department, 2001-2002
Advisor - John Omdahl, PhD
Project - Expression, characterization, and selective inhibition of ctyochrome P450 C24 hydroxylase. - Sandia National Laboratories, Material Science and Technology Department, 1999-2002
Advisor - Kamyar Rahimian, PhD
Project - Design and synthesis of non-shrinking polycarbosiloxane gels based on the ring-opening polymerization of monomers with two disilaoxacylcopentane groups.
In the laboratory of Rick Moss, I am currently working on the extraction and purification of mouse cardiac myofibrillar proteins for comparative proteomics by mass spectroscopy. CAREER GOAL - The heart of my scientific interests captures the molecular basis of experimental pathology. Nothing intrigues me more than the elucidation of mechanisms governing the initiation and manifestation of human diseases, whether they arise exogenously via pathogenic infections or endogenously via mutations in the genome. On the molecular level, I am particularly drawn towards the structural and functional effects of harmful stimuli as they apply to human physiology. By adopting a comprehensive approach to the study of pathology, I am interested in developing new insights into the molecular events underlying the context of diseased states, coupling the exposure of pathogenic mechanisms to the development of novel therapeutic treatments.
PUBLICATIONS - Rahimian K, Loy DA, and Chen PP. Nonshrinking, Photopolymerizable Polycarbosiloxanes through Ring-Opening Polymerization of Disilaoxacyclopentane Monomers. Chem. Mater 17:1529-34, 2005.
- Omdahl JL, Bobronikova EV, Annalora A, Chen P, and Serda R. Expression, Structure-Function, and Molecular Modeling of Vitamin D P450s. J Cell Biochem 88:356-62, 2003.
PRESENTATIONS - Peter P. Chen, Ekaterina Bobrovnikova, Andrew Annalora, John Omdahl. Selective Inhibition of Rat Mitochondrial Cytochrome P450 C24 Hydroxylase: Mechanistic Studies for Enzyme Action. Presented at the 2002 Annual UNM Department of Biochemistry and Molecular Biology Research Retreat, Sevilleta, NM, 2002.
- Peter P. Chen, Kamyar Rahimian. Siloxane-Bridged Disilaoxacyclopentanes as Precursors to Non-Shrinking Polysiloxane Gels. Presented at the 17th American Chemical Society Rocky Mountain Regional Meeting, Materials Symposium: Bio/Polymers, 2002.
- Peter P. Chen, Kamyar Rahimian, Douglas A. Loy. Butylene-Bridge Disilaoxacyclopentanes: Liquid Precursors for Non-Shrinking Polycarbosiloxanes. Presented at the 222nd American Chemical Society National Meeting and Exposition, Division of Polymer Chemistry, 2001.
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