Home » Research » Resources Home Director Intro Structure Timeline Med 1 & 2 Grad School Med 3 & 4 Funding Directors/Administrators Committees Research Training Programs Faculty By Name Faculty By Program Resources History Campus Resources Students Research Highlights Students by Name Students by Year Resources Alumni By Name By Degree By Year Publications Admissions Procedure Application Living in Madison Housing Dining Campus Tour City Current Events Seminar Symposium Retreat Contact Us Resources Shared resources Numerous shared-use facilities across campus greatly enhance opportunities for learning cutting-edge methodology and application of such technology to research problems. MSTP trainers who wish to learn new methods or apply new techniques to their investigations can go to shared-use facilities for expert guidance from the trained staff, as well as access the necessary instrumentation. Members of the active MSTP training faculty have played major roles in development of the facilities. Facilities of particular use to MSTP trainees are briefly described below. The Biotechnology Center provides contract services for DNA sequencing and synthesis; DNA microarray production, processing and analysis; yeast two-hybrid interaction screening; mass spectrometric and proteomic services; a transgenic mouse and rat facility; and a plant biotechnology lab. The Center also houses the Biology New Media Center, which provides computing resources for instructional and research use and houses an NSF-funded rapid prototyping machine (Z Corporation) for generating physical models of three-dimensional molecular structures. The National Magnetic Resonance Facility at Madison maintains nine modern spectrometers, with field strengths ranging from 400-900 MHz and equipped for the most demanding multi-dimensional, multi-nuclear spectroscopic applications. NMRFAM is directed by John Markley, a MSTP trainer, and has a staff of 15 who carry out their own research and make new technologies available to service users and collaborators. The facility also supports in vivo and ex vivo experiments for physiological and micro-imaging analysis, utilizing a 400 MHz wide-bore spectrometer that can accommodate organisms as large as a rat. The NIH-funded BioMagResBank (an outreach arm of NMRFAM) compiles and maintains the growing NMR structural database for researchers worldwide. The NSF- and NIH-funded Biophysics Instrument Facility houses an isothermal titration calorimeter, differential scanning calorimeter, analytical ultracentrifuge, circular dichroism spectrometer, Fourier transform infrared spectrometer, and surface plasmon resonance detector. This ensemble of instruments enables thorough characterization of conformation, structure, and complexation of macromolecules. The facility is directed by Ron Raines, a MSTP trainer, and supervised by an Instrumentation Specialist who helps students perform their experiments. The Flow Cytometry Lab is located in the Clinical Sciences Center and provides contract services for the entire campus. The facility owns one single-laser cytometer, two double-laser cytometers, and two triple-laser FACSVantage SE’s with cloning capability and sample temperature control. UW-Madison has extensive microscopy facilities including the Materials Science Center, the Keck Imaging Facility, and UW Microscopy & Imaging Resource (UWMIR). Among the available microscopes are four scanning electron microscopes, six transmission electron microscopes, three scanning transmission electron microscopes, and four confocal laser scanning microscopes. John White, a MSTP trainer, directs the Laboratory for Optical and Computational Instrumentation, which develops novel methods for imaging and manipulating live organisms. The Center for Eukaryotic Structural Genomics (CESG) is an NIH-funded facility for the high-throughput determination of the tertiary structure of proteins, primarily by x-ray crystallography. Julie Mitchell, a MSTP trainer, participates in this facility. The CESG carries out collaborative studies with campus laboratories.